MTX脱发尽管叶酸每周6天

CuriousSquirrel

但我知道有一些话题,我读过大多数人建议增加剂量的叶酸对甲氨蝶呤对抗脱发。我每周5毫克叶酸6 x,我认为这是比大多数人。(它是太多?我被告知要做什么,但大多数人似乎更小的剂量或更少)

我已经在10毫克注射mtx自去年11月以来,在上个月已经注意到我的头发比以前更多。今天我洗了我的头发,这是相当惊人的速度。

我错过了我上周剂量mtx。我应该有一个剂量是一周前但是我的医疗实践砸了这一切,所以我一直没有它。我希望明天捡起来,但不确定是否继续用它,因为它似乎没有帮助尽管造成现在很多疲劳和脱发。我刚开始Amgevita所以我希望最终住口!

我每天补充一些欧米伽3和一般维生素除了规定的叶酸。还有什么我可以做什么?我知道这不是最糟糕的事情会发生,但它有点令人沮丧的我的头发脱落,尤其是当我享受在它长首次在许多年!

jamieA

I know there are a few topics on this but most that I've read have people suggesting upping the dose of folic acid to combat hair loss on methotrexate. I am taking 5mg folic acid 6X a week, which I think is more than most people take. (Is it TOO much? It's what I was told to do but most people seem to take smaller doses or less frequently)<\/p>

I've been on 10mg mtx injections since November and in the last month or so have noticed my hair coming out more than it used to. Today I washed my hair and it's been coming out at quite an alarming rate. <\/p>

I actually missed my dose of mtx last week. I should have had a dose exactly one week ago but my medical practice messed everything up so I have been without it. I'm hoping to pick it up tomorrow but not sure whether to continue with it as it doesn't seem to have been helping despite causing a lot of fatigue and now hair loss. I have just started Amgevita so I was hoping to come off it eventually anyway!<\/p>

I take an omega 3 supplement daily and a general multivitamin in addition to the prescribed folic acid. Is there anything else I could be doing? I know it's not the worst thing that could happen but it is a little depressing to have my hair falling out, especially as I'm enjoying having it long for the first time in many years!<\/p>","bodyRaw":"[{\"insert\":\"I know there are a few topics on this but most that I've read have people suggesting upping the dose of folic acid to combat hair loss on methotrexate. I am taking 5mg folic acid 6X a week, which I think is more than most people take. (Is it TOO much? It's what I was told to do but most people seem to take smaller doses or less frequently)\\nI've been on 10mg mtx injections since November and in the last month or so have noticed my hair coming out more than it used to. Today I washed my hair and it's been coming out at quite an alarming rate. \\nI actually missed my dose of mtx last week. I should have had a dose exactly one week ago but my medical practice messed everything up so I have been without it. I'm hoping to pick it up tomorrow but not sure whether to continue with it as it doesn't seem to have been helping despite causing a lot of fatigue and now hair loss. I have just started Amgevita so I was hoping to come off it eventually anyway!\\nI take an omega 3 supplement daily and a general multivitamin in addition to the prescribed folic acid. Is there anything else I could be doing? I know it's not the worst thing that could happen but it is a little depressing to have my hair falling out, especially as I'm enjoying having it long for the first time in many years!\\n\"}]","format":"rich","dateInserted":"2022-06-12T22:26:20+00:00","insertUser":{"userID":118914,"name":"CuriousSquirrel","url":"https:\/\/community.versusarthritis.org\/profile\/CuriousSquirrel","photoUrl":"https:\/\/wc.vanillicon.com\/v2\/c2cdc936eb56cfd505f175be9329fffe.svg","dateLastActive":"2022-07-14T13:59:07+00:00","banned":0,"private":false},"displayOptions":{"showUserLabel":false,"showCompactUserInfo":true,"showDiscussionLink":true,"showPostLink":true,"showCategoryLink":false,"renderFullContent":false,"expandByDefault":false},"url":"https:\/\/community.versusarthritis.org\/discussion\/57819\/mtx-hair-loss-despite-folic-acid-6-days-a-week","embedType":"quote","name":"MTX hair loss despite folic acid 6 days a week"}"> https://community.versusarthritis.org/discussion/57819/mtx-hair-loss-despite-folic-acid-6-days-a-week

嗨@CuriousSquirrel

我对MTX和Amgevita我穿上在今年年初维生素D3。并不是与脱发——我没有太多,但它出现在我的血液测试,我低D3 -应该是最低水平的一半。列出的症状之一D3缺乏是脱发。你拿一个质子泵抑制剂奥美拉唑等?我读过一些研究表明质子泵抑制剂会导致维生素D的减少。

stickywicket

@jamieA使一个很好的观点关于维生素d .我认为NHS建议我们都应该在秋季和冬季的补充,因为我们没有得到足够的阳光在英国。https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-d/

然而,它还说,大多数人失去了一天50 - 100根头发,经常没有注意到它。也许你注意到当你增长你的头发。失去是很正常的头发。https://www.nhs.uk/conditions/hair-loss/

叶酸是减轻对冰毒的副作用。我的理解是,它也减少了一个小的良好效果,所以我们如果我们能更好管理上更少的叶酸。

CuriousSquirrel

https:\/\/community.versusarthritis.org\/discussion\/57819\/mtx-hair-loss-despite-folic-acid-6-days-a-week<\/a><\/p>

Hi @CuriousSquirrel<\/a> <\/p>

I'm on MTX and Amgevita and I was put on to vitamin D3 at the start of the year. It wasn't anything to do with hair loss - I don't have much - but it showed up in my blood tests that I was low in D3 - about half what should be the minimal level. One of the symptoms listed for D3 deficiency is hair loss. Do you take a proton pump inhibitor such as Omeprazole ? I've read a couple of studies that show that PPIs can cause a reduction in vitamin D.<\/p>","bodyRaw":"[{\"insert\":\"https:\\\/\\\/community.versusarthritis.org\\\/discussion\\\/57819\\\/mtx-hair-loss-despite-folic-acid-6-days-a-week\",\"attributes\":{\"link\":\"https:\\\/\\\/community.versusarthritis.org\\\/discussion\\\/57819\\\/mtx-hair-loss-despite-folic-acid-6-days-a-week\"}},{\"insert\":\"\\n\"},{\"insert\":\"Hi \"},{\"insert\":{\"mention\":{\"name\":\"CuriousSquirrel\",\"userID\":118914}}},{\"insert\":\" \\nI'm on MTX and Amgevita and I was put on to vitamin D3 at the start of the year. It wasn't anything to do with hair loss - I don't have much - but it showed up in my blood tests that I was low in D3 - about half what should be the minimal level. One of the symptoms listed for D3 deficiency is hair loss. Do you take a proton pump inhibitor such as Omeprazole ? I've read a couple of studies that show that PPIs can cause a reduction in vitamin D.\\n\"}]","format":"rich","dateInserted":"2022-06-13T08:18:04+00:00","insertUser":{"userID":116922,"name":"jamieA","url":"https:\/\/community.versusarthritis.org\/profile\/jamieA","photoUrl":"https:\/\/w3.vanillicon.com\/v2\/3589cb057d719443275bc889abf51573.svg","dateLastActive":"2023-06-23T20:25:24+00:00","banned":0,"private":false},"displayOptions":{"showUserLabel":false,"showCompactUserInfo":true,"showDiscussionLink":false,"showPostLink":false,"showCategoryLink":false,"renderFullContent":false,"expandByDefault":false},"url":"https:\/\/community.versusarthritis.org\/discussion\/comment\/696020#Comment_696020","embedType":"quote"}"> https://community.versusarthritis.org/discussion/comment/696020 Comment_696020

谢谢你的回复。我的维生素D测试最近,感觉不错。我与RDA的100%每天服用多种维生素D和我不服用质子泵抑制剂。

我也在户外工作和我的最爱好户外活动所以我很少里面!所以我不认为缺乏维生素D是在这种情况下,但它肯定是我会留意的。

CuriousSquirrel

@jamieA<\/a> makes a good point about Vit D. I think the NHS recómmends we should all take a supplement in autumn and winter as we don't get enough sun in UK. https:\/\/www.nhs.uk\/conditions\/vitamins-and-minerals\/vitamin-d\/<\/a><\/p>

However, it also says that most people lost 50-100 hairs a day, often without noticing it. Maybe you're noticing it more as you're growing your hair. It's normal to lose hair. https:\/\/www.nhs.uk\/conditions\/hair-loss\/<\/a><\/p>

Folic acid does mitigate against side effects of meth. My understanding is that it also diminishes a little the good effects of it so we're better off if we can manage on less folic acid.<\/p>","bodyRaw":"[{\"insert\":{\"mention\":{\"name\":\"jamieA\",\"userID\":116922}}},{\"insert\":\" makes a good point about Vit D. I think the NHS recómmends we should all take a supplement in autumn and winter as we don't get enough sun in UK. \"},{\"attributes\":{\"link\":\"https:\\\/\\\/www.nhs.uk\\\/conditions\\\/vitamins-and-minerals\\\/vitamin-d\\\/\"},\"insert\":\"https:\\\/\\\/www.nhs.uk\\\/conditions\\\/vitamins-and-minerals\\\/vitamin-d\\\/\"},{\"insert\":\"\\nHowever, it also says that most people lost 50-100 hairs a day, often without noticing it. Maybe you're noticing it more as you're growing your hair. It's normal to lose hair. \"},{\"attributes\":{\"link\":\"https:\\\/\\\/www.nhs.uk\\\/conditions\\\/hair-loss\\\/\"},\"insert\":\"https:\\\/\\\/www.nhs.uk\\\/conditions\\\/hair-loss\\\/\"},{\"insert\":\"\\nFolic acid does mitigate against side effects of meth. My understanding is that it also diminishes a little the good effects of it so we're better off if we can manage on less folic acid.\\n\"}]","format":"rich","dateInserted":"2022-06-13T09:18:05+00:00","insertUser":{"userID":15071,"name":"stickywicket","url":"https:\/\/community.versusarthritis.org\/profile\/stickywicket","photoUrl":"https:\/\/w9.vanillicon.com\/v2\/9fdd062ad197cafded2e18137c05f5c8.svg","dateLastActive":"2023-06-23T20:36:53+00:00","banned":0,"private":false},"displayOptions":{"showUserLabel":false,"showCompactUserInfo":true,"showDiscussionLink":false,"showPostLink":false,"showCategoryLink":false,"renderFullContent":false,"expandByDefault":false},"url":"https:\/\/community.versusarthritis.org\/discussion\/comment\/696027#Comment_696027","embedType":"quote"}"> https://community.versusarthritis.org/discussion/comment/696027 Comment_696027

谢谢你的回复@stickywicket。我没有被告知,叶酸可以减少mtx的影响。会尽量少服用叶酸mtx迄今为止对我无用!

我肯定是掉头发以更快的速度比一天50 - 100。当我将回来感觉那么瘦,我本能地四处寻找,试图找到剩下的。谢天谢地它很厚一开始所以大多数人可能没有注意到但我绝对做的,并以这种速度会在几个月后了。我失去了很多的头发由于另一个疾病很多年前我记得很多我做的研究。它不是与药物虽然和我使用的解决方案,现在时间不工作!

stickywicket

请不要改变任何处方药物由于我写的东西。这是至关重要的我们咨询医生在这些东西上。我可能是错的。(我经常)他们有多年的学习。

我明白了,如果你有头发问题在过去,你会担心你的。但是有很多东西会影响头发,发质。疾病本身的一个开始。

如果你定期血液测试表明,炎症标记物仍然很高然后你的风湿病学家可能需要调整药物。但是,如果这仅仅是你正在经历的痛苦,你的医生可以处理它。

CuriousSquirrel

Please don't change any prescribed meds as a result of anything that I've written. It's essential we consult our medics on these things. I could be wrong. (I often am😁<\/span>) They are the ones who have put in years of learning. <\/p>

I understand that, if you've had hair problems in the past, you will be anxious about yours. But there are so many things that can affect hair and hair quality. Ill-health itself for a start.<\/p>

If your regular blood tests show that your inflammatory markers are still high then your rheumatologist might want to tweak your meds. But, if it's simply pain you are experiencing, your GP can deal with it.<\/p>","bodyRaw":"[{\"insert\":\"Please don't change any prescribed meds as a result of anything that I've written. It's essential we consult our medics on these things. I could be wrong. (I often am\"},{\"insert\":{\"emoji\":{\"emojiChar\":\"😁\"}}},{\"insert\":\") They are the ones who have put in years of learning. \\nI understand that, if you've had hair problems in the past, you will be anxious about yours. But there are so many things that can affect hair and hair quality. Ill-health itself for a start.\\nIf your regular blood tests show that your inflammatory markers are still high then your rheumatologist might want to tweak your meds. But, if it's simply pain you are experiencing, your GP can deal with it.\\n\"}]","format":"rich","dateInserted":"2022-06-14T09:05:23+00:00","insertUser":{"userID":15071,"name":"stickywicket","url":"https:\/\/community.versusarthritis.org\/profile\/stickywicket","photoUrl":"https:\/\/w9.vanillicon.com\/v2\/9fdd062ad197cafded2e18137c05f5c8.svg","dateLastActive":"2023-06-23T20:36:53+00:00","banned":0,"private":false},"displayOptions":{"showUserLabel":false,"showCompactUserInfo":true,"showDiscussionLink":false,"showPostLink":false,"showCategoryLink":false,"renderFullContent":false,"expandByDefault":false},"url":"https:\/\/community.versusarthritis.org\/discussion\/comment\/696057#Comment_696057","embedType":"quote"}"> https://community.versusarthritis.org/discussion/comment/696057 Comment_696057

我想我的机会通过任何人询问叶酸本月很小!风湿病学的护士总是擅长刷牙一边别的副作用,甚至当他们众所周知的(这样!)

我所有的过去的血液测试是正常的,尽管我没有一个一段时间,现在我有了三个月而不是每月。也通过GP是无望的。他们从来没有能够为疼痛过去做任何事!我想我可能非常不幸的住在这里。我不相信任何这些服务,其他人似乎有这样的信心。他们让我失望了,骗了我很多次。

stickywicket

很好,你在3个月的血液,这意味着一切都稳定。我对他们已经很久除了奇怪的轻微波动,当我被要求重复。

副作用的问题在于,很多是常见的几乎所有药物。读过传单。我认为这是非常重要的,我们需要注意的。

NHS说我们应该小心当我们在冰毒服用补充剂。特别是,他们说,不采取任何,包括叶酸(叶酸)如果你已经把它。https://www.nhs.uk/medicines/methotrexate/

至于痛苦,我不希望没有它。药剂师可以建议会适当给你其他任何你正在服用处方药物或补品。

CuriousSquirrel

It's good that you're on 3-monthly bloods as that means things are stable. I've been on them for yonks apart from the odd slight blip when I've been asked to repeat one. <\/p>

The trouble with side-effects is that so many are common to virtually all meds. Read any leaflet. i think it's the really important ones we need to take note of.<\/p>

NHS does say we should be careful about taking supplements when we're on meth. Especially, they say, don't take any that include folic acid (folate) if you're already taking it. https:\/\/www.nhs.uk\/medicines\/methotrexate\/<\/a><\/p>

As for pain, I don't expect to be without it. You pharmacist could advise on what would be appropriate given any other prescribed meds or supplements you're taking.<\/p>","bodyRaw":"[{\"insert\":\"It's good that you're on 3-monthly bloods as that means things are stable. I've been on them for yonks apart from the odd slight blip when I've been asked to repeat one. \\nThe trouble with side-effects is that so many are common to virtually all meds. Read any leaflet. i think it's the really important ones we need to take note of.\\nNHS does say we should be careful about taking supplements when we're on meth. Especially, they say, don't take any that include folic acid (folate) if you're already taking it. \"},{\"attributes\":{\"link\":\"https:\\\/\\\/www.nhs.uk\\\/medicines\\\/methotrexate\\\/\"},\"insert\":\"https:\\\/\\\/www.nhs.uk\\\/medicines\\\/methotrexate\\\/\"},{\"insert\":\"\\nAs for pain, I don't expect to be without it. You pharmacist could advise on what would be appropriate given any other prescribed meds or supplements you're taking. \\n\"}]","format":"rich","dateInserted":"2022-06-16T09:08:31+00:00","insertUser":{"userID":15071,"name":"stickywicket","url":"https:\/\/community.versusarthritis.org\/profile\/stickywicket","photoUrl":"https:\/\/w9.vanillicon.com\/v2\/9fdd062ad197cafded2e18137c05f5c8.svg","dateLastActive":"2023-06-23T20:36:53+00:00","banned":0,"private":false},"displayOptions":{"showUserLabel":false,"showCompactUserInfo":true,"showDiscussionLink":false,"showPostLink":false,"showCategoryLink":false,"renderFullContent":false,"expandByDefault":false},"url":"https:\/\/community.versusarthritis.org\/discussion\/comment\/696129#Comment_696129","embedType":"quote"}"> https://community.versusarthritis.org/discussion/comment/696129 Comment_696129

我检查我的风湿病学家,顾问,风湿病学护士和药物顾问向我展示了如何使用甲氨蝶呤和他们都说这是好这些补充剂,我多年来一直在没有脱发。如果这四个“专家”都是错误的,我真的不知道谁可以信任。这是为数不多的几个不同的人之间的信息的一致和我交谈的NHS。很多次我有了相互矛盾的信息,但他们都同意这些补充剂是好的。

我不明白这个不愿相信甲氨蝶呤可以造成任何副作用。这是我的一个主要担忧开始药物——没有人会认真对待的副作用,在这里再次发生。

我以煤气灯照明的,被我的风湿病学家,当我有一段时间持续5周后增加我的mtx剂量。她说这只是一个巧合。我降低了剂量,它立刻就停了。再次加大了剂量,再次开始。再次降低剂量,又停了下来。讨论忽视显而易见的。我没那么傻。

很多人从甲氨蝶呤脱发,许多人停止服用它,因为,很多不能忍受它。我不喜欢被当作傻瓜,这是我最后一次在这里发布。

jamieA

嗨@CuriousSquirrel

我很抱歉你有这样的感觉,我认为没有人是想对待你就像个白痴。我认为许多在MTX遭受的副作用。在我的例子中我继续遭受相当衰弱的疲劳一天或两天之后我的MTX的一天。这真的是像关掉开关——我可以中期狗走,不得不停下来休息,只发生在那些日子。我20毫克MTX的时候遭受了失去平衡。我也严重发作了心房纤颤和心动过速需要蓝光救护车旅程——我以前从来没有这样的事情在我的生命中。然后我再次遭受住院治疗4个月后与心动过速。在这一点上我的MTX减少到10毫克。我没有受到一集——9个月和计数。医生我处理相当怀疑因果但拖网互联网医学论文带来了大量的论文文档实例。 I'd suggest you might try this for your symptoms and then talk to your medics.

一个点我让Amgevita关于移动。当我这样做我觉得自从我柳氮磺胺吡啶摄入量和柳氮磺胺吡啶和MTX摄入量没有工作然后当Amgevita我放弃其他两个。风湿病学家说它没有这样的推定是这三种药物的混合物为我工作。

20个月以来这发生在我身上我意识到一个孤独的疾病可以由covid更糟。即使有最好的亲密的家庭和朋友给我的意图并不总是理解发生了什么。我不能做我用于社交,绕过,积极享受生活的方式。我见过许多医生一直矛盾或(在我的第一个风湿病学家和我的一些GPs和员工)傲慢而无益的。有时觉得推水上山。至少在这里你可以与在类似的情况下并从其他人那里获得建议。这个建议可能并不总是相关的但至少提供诚信。

stickywicket

我似乎已经冒犯了你,如果是这样的话,我真的很抱歉。如果你发现论坛帮助请不要停止发布。我将采取不回答任何你的帖子。

只是为了别人阅读的好处,我相信你的医生是对的。(你的第一段。)NHS的网站必然是通用而你的人知道你的病史,可以具体的建议。

TUL50

脱发影响每个人都不同,你显然是痛苦的。更痛苦的是专家们都被模糊的副作用。

每年的这个时候,你可以看到更多的脱发,因为很热,所以我们正面一些体重下降的头发,这是一个自然循环看到不少头发堵塞塞孔。然而,如果你正在失去大片的头发,秃头补丁,这个问题需要解决。

你不想要更多的药物,你只是想要有人和你说实话为什么伟大的蜕皮情况和如何防止进一步的损失。我希望你能够得到这些答案。

就我个人而言,我两年前经历化疗,失去了我的头发。一切。睫毛和眉毛——BEST.TIME.EVER !我喜欢做一个秃子,因为我没有受到无休止的糟糕的发型我现在如果在块开始下降,因为我对MTX和叶酸,我将到达快船和解决自己的问题。