Methotrexate side effects

MrsH
MrsH MemberPosts:3
edited 21. Dec 2021, 12:02 inSay Hello

Hi all

I am back on Methotrexate after being of it for a couple of years. I’m on my second week and today I have been totally floored by let’s say visiting the ladies room far too often!

can anyone advise what might help to calm this symptom? It happened alittle yesterday but today is a different story. I haven’t been able to eat today as I’m so scared of it not staying in my stomach.

thank you for any advice

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  • Ellen
    Ellen ModeratorPosts:1,007

    Good morning@MrsH. Welcome to the Versus Arthritis Online Community.

    我看到你回我thotrexate after a gap of 2 years and are having some rather nasty and debilitating side effects.

    As you can see from this article diarrhoea is listed as a side effect:

    I've had a bit of a look back to see whether anyone else has had the problem as severely as you and found this old thread:


    \nI was diagnosed three months ago. I'm 46 now, the same age as my maternal grandmother when she was diagnosed.

    \nI've been reading up on the site which has been very helpful. I was started on the triple therapy but reacted to two of the drugs, leaving me on methotrexate but it looks like this may have been the culprit. I'm on 15mg with the idea of building up to 20mg next week, however the day after I take it I start with severe stomach cramps and diarrhoea. This week it's worse than ever but I'm scared to call my local RA helpline as I've had to call every week so far as I've reacted to the medication and last time I called I got the distinct impression they thought I was being tiresome and should put up with all this.

    \nIs this reaction to methotrexate normal, my new boss at work is threatening to put me on a disciplinary because I had to leave an interview to use the loo. \":(\"<\/img>","bodyRaw":"Hello everyone. :autumn-sun: \n\nI was diagnosed three months ago. I'm 46 now, the same age as my maternal grandmother when she was diagnosed.\n\nI've been reading up on the site which has been very helpful. I was started on the triple therapy but reacted to two of the drugs, leaving me on methotrexate but it looks like this may have been the culprit. I'm on 15mg with the idea of building up to 20mg next week, however the day after I take it I start with severe stomach cramps and diarrhoea. This week it's worse than ever but I'm scared to call my local RA helpline as I've had to call every week so far as I've reacted to the medication and last time I called I got the distinct impression they thought I was being tiresome and should put up with all this. \n\nIs this reaction to methotrexate normal, my new boss at work is threatening to put me on a disciplinary because I had to leave an interview to use the loo. :(","format":"bbcode","dateInserted":"2016-11-06T12:43:28+00:00","insertUser":{"userID":107855,"name":"XantheD","url":"https:\/\/community.versusarthritis.org\/profile\/XantheD","photoUrl":"https:\/\/w1.vanillicon.com\/v2\/161c46e2a1c8d4848ed47759facafb68.svg","dateLastActive":"2016-11-11T17:05:34+00:00","banned":0,"punished":0,"private":false},"displayOptions":{"showUserLabel":false,"showCompactUserInfo":true,"showDiscussionLink":true,"showPostLink":true,"showCategoryLink":false,"renderFullContent":false,"expandByDefault":false},"url":"https:\/\/community.versusarthritis.org\/discussion\/47248\/hi-new-and-suffering-on-methotrexate-help","embedType":"quote","name":"Hi new and suffering on methotrexate help!"}"> https://community.versusarthritis.org/discussion/47248/hi-new-and-suffering-on-methotrexate-help

    我宁愿您需要就这个问题接受一些医疗建议,尤其是如果您不吃东西,那对您根本不利。

    Our helpline might also be able to help:


    Hopefully one of our members will be along to share their tips too.

    请让我们知道您的情况

    艾伦。

  • MrsH
    MrsH MemberPosts:3

    Hi@Ellen

    Thank you for the information. I have a call back with the doctor this morning so hopefully they will be able to give me something.

    have a great day and Merry Christmas

    Alison

  • Ellen
    Ellen ModeratorPosts:1,007
    edited 21. Dec 2021, 09:14

    That's good Alison

    手指交叉DR有一些帮助。

    最好的祝愿和圣诞快乐。

    艾伦。

  • @MrsHI had the same issue, I accidentally found having a large coffee before & after MTX seemed to lessen the affects considerably.

    Now wondering if the subcut injection is any better.

  • Denise
    Denise MemberPosts:4

    I found the injections were better for me, less side effects and really easy to do.

  • jul29
    jul29 MemberPosts:2

    嗨,这里是新的,

    i been taking methotrexate for 3 years now, due to visit my consultant next week , just wondered how others get on .

    i,ve recently had my fingers seem more swollen and can’t wear most my rings but manage to keep my wedding ring on for now and have read that the tablets can cause knuckles to swell ? Or is this just progression of RA ?

    also had chest infection and shingles recently maybe related when you start looking into RA etc and had the 4th covid jab with the worst side effects of them all Not long before being I’ll, doctor thinks as each jab made me run down and build up , not being able to recover fully. I had a week of methatrexate and off work and felt most energy had in ages. Back on pill again and work and tired again .

    Just wonder how do others get on with all these and if similar

    thanks julia

  • anneb82
    anneb82 AdministratorPosts:263

    Hi@jul29

    欢迎to the online community and thank you for joining us. I hope that you find this a friendly place to continue sharing.

    因此,听起来您经历了艰难的时光,而您的Covid助推器,胸部感染和带状疱疹以及RA也是如此。在过去的三年中,您一直在服用甲氨蝶呤,但最近发现您的手指看起来更肿胀,并读到平板电脑会导致您的指关节肿胀。您想知道这是正确的还是RA的自然发展。

    I'm not sure about the methotrexate affecting someone's knuckles. Its not something that I ever experienced myself but that's not to say that others haven't experienced it. I would be interested in seeing what other members think and have experienced and think that's it will be of interest to many others.

    I have include the information below that I think may be of use to you. It may be something that you have already seen, but hopefully you will find it interesting.

    请让我们知道您本周与顾问的约会,祝您好运。

    Take care

    Anne (Moderator)

  • 我已经服用甲氨蝶呤已有4年了,并且经验丰富。脱发(正如我不建议叶酸的建议)和大量前往厕所的旅行,但几个月后就安定下来。

    我2年前进行了CT扫描,他们在我的肺中发现了一个10mm的“结节”,并被告知这是RA的症状,可能服用甲氨蝶呤。建议我停止服用。我的顾问说,这将消失,但我没有给我这个类固醇。

    So in January this year I was told it was now 12mm and enough to cause concern so surgeon agreed it was best to remove.

    I am now looking to find an alternative so have decided to take磺胺嗪so fingers crossed this works!

  • 海伦
    海伦 AdministratorPosts:44

    Hi@Tricia_F

    Thanks for joining the Online Community, and welcome!

    You may just be looking for some advice and support, well you've come to the right place 

    您可能会在我们的网站上找到以下有关类风湿关节炎(RA)的页面,有很多信息也提供有关如何管理状况的提示。许多患有RA的人需要服用多种药物,因为不同的药物以不同的方式起作用。

    As you've already found, drug treatments may be changed from time to time. This can depend on how bad your symptoms are, or because something relating to your condition has changed.

    Hopefully this information will be useful to you.

    Rheumatoid arthritis | Causes, symptoms, treatments (versusarthritis.org)

    请随时让我们知道您的情况。

    Best wishes

    海伦

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