Primary Care Centre Versus Arthritis
Musculoskeletal problems represent the single largest group of chronic conditions for which patients consult their GPs. The Primary Care Centre Versus Arthritis is focused on reducing the existing wide variation of care, treatment and overall management of musculoskeletal conditions.
Research at this centre will focus on some of the most common musculoskeletal problems seen in primary care. These include osteoarthritis and chronic musculoskeletal pain, gout and polymyalgia rheumatica.
该中心于2008年被授予基尔大学，并于2013年续签了五年。
Website:www.keele.ac.uk
生物力学和生物工程研究中心与关节炎beplay体育怎么下载
This centre is based at the University of Cardiff and brings together experts in engineering, biomedical science, orthopaedics, rheumatology and physiotherapy to apply engineering solutions and basic science to the many problems caused by arthritis.
Research at this centre is focussed on investigating whether altering joint biomechanics can reduce excessive stresses on the joint, preventing or reversing the development of arthritis.
The centre also hopes to identify indicators of rapid onset of arthritis following injury, develop interventions to prevent disease development and progression, and develop tools to predict treatment outcomes, allowing the right treatment to be given to the right patient.
The outcomes of this research will inform and direct diagnosis and rehabilitation and identify new therapies for the treatment of osteoarthritis and back pain.
在早期阶段的治疗应减少因关节炎影响关节的损害，并通过开发新方法来防止重复伤害和帮助康复，使关节伤害受益。
该中心最初是在2009年授予的，并于2015年续签了五年的第二学期。
Website:www.cardiff.ac.uk
疼痛中心与关节炎beplay体育怎么下载
The centre based at the University of Nottingham, brings together healthcare professionals and research scientists from different fields to create a national centre for research into understanding the mechanisms of pain in arthritis.
研究在这一中心目标to better understand the biological basis of pain in osteoarthritis, to develop new drugs to treat pain more effectively and use a more targeted treatment approach for individuals.
Alongside this research, the centre is investigating the basic pathways of pain perception and the changes in the tissues caused by arthritis to identify new targets for developing treatments. This research should help us to develop clinical trials which address the major concerns of people with arthritis pain.
This centre was originally awarded in 2010 and renewed for a second period of five years in 2015.
Website:www.nottingham.ac.uk
组织工程和再生疗法中心与关节炎beplay体育怎么下载
This centre brings together clinicians and scientists from the fields of engineering, biology and material science with the aim of regenerating bone and cartilage by using the patients’ own stem cells to repair joint damage caused by osteoarthritis. The centre brings together expertise from Cambridge, Aberdeen, Newcastle, York, Keele and Oswestry.
Current treatments for early osteoarthritis are usually limited to non-surgical options such as pain killers and physiotherapy. Patients undergo joint replacement operations once the disease has progressed to joint failure, which involves major surgery and has associated risks.
研究在这一中心目标to alleviate suffering at an early stage in disease by introducing novel treatments into damaged joints, and repairing damage through less invasive operations such as key-hole surgery.
This centre was originally awarded in 2011 and was renewed for a second term of five years in 2016.
MRC Versus Arthritis Centre for Musculoskeletal Ageing Research
Both the MRC and the charity recognise that musculoskeletal ageing presents significant challenges to individuals, their families/ carers and the whole of the UK (socially and economically). It is considered such an important problem that both funders chose, in 2011, to invest in two complementary centres (CIMA and CMAR).
The MRC Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR) was awarded to the Universities of Birmingham and Nottingham. Versus Arthritis contributed £625,000 and the Medical Research Council (MRC) £1,875,000, with extra support from the host institutes.
Research at this centre is focussed on understanding how and why we lose muscle, bone and cartilage as we age, and the role played by factors such as inflammation, metabolism, altered hormones and obesity in this process.
The loss of muscle, bone and cartilage as well as decreased function of the nervous system results in reduced control of movement and balance, which has a number of clinical consequences including osteoarthritis and increased risk of falls and fracture.
Researchers hope to detect the key factors which drive ageing of the cells and tissues that make up the musculoskeletal system. This will allow them to identify new drugs and lifestyle changes, such as exercise and diet, to maintain a healthy musculoskeletal system. This will reduce age related decline and keep individuals healthy and active for longer.
Website:http://cmar.online/
MRC与beplay体育怎么下载关节炎中心用于肌肉衰老的综合研究
Both the MRC and the charity recognise that musculoskeletal ageing presents significant challenges to individuals, their families/ carers and the whole of the UK (socially and economically). It is considered such an important problem that both funders chose, in 2011, to invest in two complementary centres (CIMA and CMAR).
与医学研究委员会beplay体育怎么下载（MRC）合作，将MRC与关节炎综合研究中心（CIMA）授予利物浦，纽卡斯尔和谢菲尔德大学。beplay体育怎么下载与关节炎相比，贡献了62.5万英镑和MRC£1,875,000，并得到了东道机构的额外支持。
研究在这一中心目标to understand why our musculoskeletal system functions less well as we age and why older people develop conditions such as arthritis, osteoporosis and muscle weakness.
The centre also focusses it research on preventing and treating deterioration of the musculoskeletal tissues that occur as we age to help preserve mobility and independence in older people and thereby improving their quality of life.
Website:http://www.cimauk.org/
Centre for Adolescent Rheumatology Versus Arthritis
青少年风湿病与关节炎中心是世界上第一个致力于了解青少年关节炎的中心。beplay体育怎么下载与大奥蒙德街医院，伦敦大学学院和伦敦大学医院合作，并与大奥蒙德街医院儿童慈善机构（GOSHCC）提供资金，该中心的研究将探讨关节炎如何以及为什么影响该年龄段的人群。
Having arthritis during adolescence is not easy and it is vital that teenagers with healthcare problems are given the best treatment to address their particular needs.
该中心的任务是通过进行尖端研究来了解关节炎的发展和为什么在这个年龄段的发展和发展过程中，以改善关节炎青少年的健康和福祉。
This should lead to the discovery of new or better treatments as well as methods to prevent complications that adolescents with arthritis develop in later life (such as heart disease) and tests that may predict how the disease will progress.
该中心还将有助于提高人们对风湿病疾病青少年的健康需求的认识，并确保青少年不间断且完全获得临床试验的机会，从而使他们获得最新的治疗方法。该中心还提供教育，培训和国家网络，以增加该地区的专家数量。
运动，运动和骨关节炎研究中心与关节炎beplay体育怎么下载
该中心与牛津大学，南安普敦，巴斯，拉夫堡和利兹大学一起位于诺丁汉大学NHS NHS信托基金会。
The consortium is strengthened by several international collaborators, utilising expertise from Sweden, The Netherlands, Australia and USA.
该中心汇集了运动医学和骨关节炎的专家，以了解运动，运动，损伤，康复和骨关节炎之间的关系。
Research at this centre is focussed on gaining better insight into the development of osteoarthritis following sport and exercise injury and the risk factors associated with this. The research aims to provide everyday exercisers, recreational sportsmen and sportswomen, and elite athletes with up to date, evidence-based advice and information about taking part in sport and exercise so they can reduce their risk of injury and development of osteoarthritis.
骨关节炎发病机理与关节炎中心beplay体育怎么下载
迄今为止，骨关节炎的研究在很大程度上仅限于研究晚期疾病中发生的过程。骨关节炎发病机理的中心基于牛津大学，其研究旨在提高我们对骨关节炎为什么发展，识别新型疾病靶标的理解，包括可用于预测疾病发展和进展的标记，并创建用于诊断新成像技术的标记早期疾病。
Research into Inflammatory Arthritis Centre Versus Arthritis
该中心汇集了来自格拉斯哥，伯明翰和纽卡斯尔大学的专业知识。他们的研究专注于理解导致类风湿关节炎发展的是什么，为什么炎症持续存在以及为什么它会攻击关节。
研究人员将研究类风湿关节炎，他们产生的化学物质以及关节组织本身如何反应的各种不同细胞。
它们使用一系列不同的技术和关节炎模型，旨在创建导致疾病持续存在并使用这些信息进一步了解类风湿关节炎的分子数据库，从而导致新的和更有效的治疗方法。
Website:www.race-gbn.org
遗传学与基因组学与关节炎中心beplay体育怎么下载
该中心位于曼彻斯特大学。The aim of their research is to understand the role of genetic factors in determining whether particular people are at risk of developing inflammatory arthritis and what happens when they do.
关节炎是一种复杂的条件感病体ibility is determined by a combination of genetic and environmental or lifestyle factors. This centre focuses on rheumatoid arthritis, psoriatic arthritis and juvenile idiopathic arthritis.
该中心的研究人员与国际合作者一起为大型遗传研究做出了贡献，这些研究已经确定了与这些疾病相关的许多遗传危险因素。现在，该中心的研究人员面临着更详细检查这些风险区域的巨大挑战，以确定遗传密码的细微变化如何影响疾病过程。
Centre for Epidemiology Versus Arthritis
该中心位于曼彻斯特大学。他们的研究重点是研究特定人群中肌肉骨骼条件的原因和进展以及对治疗的反应。特别关注炎性关节炎（例如类风湿关节炎和银屑病关节炎）和骨关节炎。
Information such as previous medical history, disease severity and treatment will be collected from existing groups of patients, as well as large national databases of electronic health records, in order to develop new treatment strategies, such as computerised tools. This will guide treatment decisions and allow clinicians to target therapies to patients who are most likely to respond, leading to better patient outcomes.
MRC Versus Arthritis Centre for Musculoskeletal Health and Work
This centre is led from Southampton with partners from the Universities of Aberdeen, Lancaster, Liverpool, Oxford, Manchester, Salford, Guy’s and St Thomas’ NHS Foundation Trust and Imperial College, London.
Research at this centre brings focused on addressing major research questions to reduce the impact of musculoskeletal disorders, such as back pain and arthritis, in the workplace.
背痛，关节炎和其他肌肉骨骼疼痛的状况是英国丧失工作能力的主要原因，每年损失1000万个工作日，损失了70亿英镑。
This centre aims to identify cost-effective ways to minimise the impact of musculoskeletal conditions in the workplace and establish a national resource for advice on musculoskeletal health and work, accessible to Government, employers, workers, health professionals and patients, and actively promote best work and clinical practice.
Website:www.mrc.soton.ac.uk